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State, Territorial, and Local IC Program: Wave 2

Wave 2 builds on the Implementation Center Program by supporting a new set of targeted pilot projects designed to advance modern, standards based public health data exchange. Relaunched in 2026, Wave 2 reflects updated program priorities and timelines and focuses on four priority use cases that offer public health agencies opportunities to test and scale innovative data exchange approaches.

Data Modernization Implementation Center Program

Use Cases

The table below summarizes the Wave 2 priority use cases and proposed pilot opportunities. Pilot activities and funding approaches are currently being developed in collaboration with CDC and are subject to change.

Use Case Proposed Pilots
Chronic Disease
  • Create one standardized chronic care dataset that can be collected once through a trusted data intermediary and reused for STLT surveillance, HRSA UDS+ improvement, and NCQA/CMS-aligned digital measures.
  • Additional work may focus on high-impact barriers to chronic disease control (transportation, food insecurity, housing) and tests bi-directional closed-loop outcomes through intermediary-enabled exchange.
Maternal Child Health
  • Create longitudinal datasets for health data from pregnancy through infancy.
  • Additional work may include linking maternal and infant vital records to clinical history to improve speed and accuracy of surveillance.
Cancer Reporting
  • Use FHIR to automate reporting of cancer cases from EHRs to Cancer Registries.
  • Use AI to assist with cancer case validation.
  • Use HDU pre-filtering to reduce AIMS burden for cancer reporting.
  • Enhance pathology-driven cancer reporting.
Biothreat Radar Detection
  • Leverage HIEs/HDUs to link BioThreat Radar-funded genomic data with clinical data for actionable surveillance information.

Wave 2 Participation and Next Steps

The Wave 2 expression-of-interest period has closed. Participating jurisdictions have been selected and will be announced after remaining program approvals are complete.

Additional information about Wave 2 activities, participating jurisdictions, and program updates will be shared as details are finalized.

For general questions about the IC Program, please contact phdmic@astho.org.