The New York City Department of Health and Mental Hygiene’s Center for Population Health Data Science (CPHDS) is strengthening its data capabilities in epidemiology, public health surveillance, and informatics and investing in building data engineering, data science, and product management skills. PHIG funding enabled CPHDS to create data engineering and data product management functions to maximize the value and usefulness of data to all internal and external public health data consumers and ensure alignment between technical and organizational priorities. With its workforce in place, CPHDS has designed its cloud-based infrastructure, built the foundation for it, begun securing it to ingest public health data, and delivered data pipelining tools and a development environment to a central team of engineers and analysts. This approach increases the agency’s long-term self-reliance and ownership of the modernized data systems currently being built.